Recognition region
The −35 hexamer (TTGACA) is a conserved sequence where RNA polymerase binds. Not all promoters contain an exact match — partial matches still carry signal.
DNA promoter analysis
PromoterLab
Submit a fragment and run the classifier to predict whether a promoter region is present.
01 / Add
Paste a DNA fragment or choose a preset from the library. Only A, C, G, T bases are accepted.
02 / Mark
The tool highlights the −35 and −10 consensus hexamers, if present, as contextual signals.
03 / Run
Submit the sequence to the classifier.
04 / Review
All past runs are saved to this session for review and export.
Ready for sequence input
Select a preset or enter a sequence, then run prediction.
The −35 hexamer (TTGACA) is a conserved sequence where RNA polymerase binds. Not all promoters contain an exact match — partial matches still carry signal.
The −10 hexamer (TATAAT or TATA) is AT-rich, making the DNA easier to melt open for transcription initiation.
The +1 site is where RNA polymerase begins synthesizing the downstream transcript. It marks the boundary of the promoter region.