PromoterLab

DNA promoter analysis

PromoterLab

Check a DNA sequence.

Submit a fragment and run the classifier to predict whether a promoter region is present.

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58 bpGC 43%TTGACA foundTATAAT found

01 / Add

Enter a sequence

Paste a DNA fragment or choose a preset from the library. Only A, C, G, T bases are accepted.

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02 / Mark

Inspect motifs

The tool highlights the −35 and −10 consensus hexamers, if present, as contextual signals.

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03 / Run

Get a prediction

Submit the sequence to the classifier.

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04 / Review

Check history

All past runs are saved to this session for review and export.

58 bp
Base CompositionGC 43% · AT 57%
A 17C 13G 12T 16
✓ −35 Box (TTGACA)✓ −10 Box (TATAAT)

Prediction Result

Ready for sequence input

Select a preset or enter a sequence, then run prediction.

Guide

Learn the key markers.

−35

Recognition region

The −35 hexamer (TTGACA) is a conserved sequence where RNA polymerase binds. Not all promoters contain an exact match — partial matches still carry signal.

−10

AT-rich region

The −10 hexamer (TATAAT or TATA) is AT-rich, making the DNA easier to melt open for transcription initiation.

+1

Transcription start

The +1 site is where RNA polymerase begins synthesizing the downstream transcript. It marks the boundary of the promoter region.